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Lyzed its impact on the modifications of histones bound at the MAGE-A1 promoters. To investigate the changes in the histone signature of MAGE-A1 promoter, it was compared in basal MCF-7 cells (no expression of MAGE-A1, Table 1) to the signature in MCF-7 cells stimulated by 5-aza-CdR with/without TSA or transfected with the expression plasmid encoding for BORIS. For these analyses we used antibodie
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E positively associated with tumor grade and ESR1, PGR, and ESR2 steroid hormone receptor expression level and negatively associated with invasive epithelial tumor cell content and tumor size. In addition, ESR2 was more highly expressed in tumors with a higher percentage of stromal cells (786 tumors with 30 to 70 invasive epithelial cells), and ESR1 wasSieuwerts et al. Breast Cancer Research 201
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Nts whose relapse was treated with first-line tamoxifen monotherapy. These patients had not received (neo) adjuvant endocrine systemic treatment. In univariate analyses, no statistically significant associations were observed between DC-SCRIPT as transformed continuous variable and PFS or clinical benefit after start of first-line treatment with tamoxifen (HR = 1.08 [0.99 to 1.18], P = 0.07 and od
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Online slot internet casino is introduced as the particular most haphazard game regarding chance enjoyed by best gamers based world broad. Gaming being a great option to help make funds, every player wishes to come to be rich through that. On the other hand, not all players can get lucky as some may possibly find yourself losing everything. This is where arrives the particular importance of unders
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Rotein TCP-1 and the `chaperonin' family of bacterial (GroEL, 60-65 kDa heat shock antigen) and eukaryotic proteins. Biochem. Int. 20:833?41. 96. Gupta, R. S. 1995. Evolution of the chaperonin families (Hsp60, Hsp10 and Tcp-1) of proteins and the origin of eukaryotic cells. Mol. Microbiol. 15: 1?1. 97. Gupta, R. S. 1995. Phylogenetic analysis of the 90 kD heat shock family of protein sequences and
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On of MAGE-A1 expressionIn order to functionally investigate the impact of BORIS on promoter settings, we examined the influence of BORIS on the activity of the methylated MAGE-A1 promoter in the context of transcription factors Ets-1 and Sp1. We transiently co-transfected methylated reporter plasmids pGL2/MAGE-A1 (-77/+183) containing the BORIS binding site located downstream of the start site (F
1
Uctal carcinoma in situ (DCIS) component or infiltrating lobular carcinoma compared with infiltrating ductal carcinomas (both P
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Mith, T. 1987. Eukaryotes with no mitochondria. Nature 326: 332?33. 30. Cavalier-Smith, T. 1987. The origin of eukaryotic and archaebacterial cells. Ann. N. Y. Acad. Sci. 503:17?4. 30a.Cavalier-Smith, T. 1991. The evolution of cells, p. 271?04. In S. Osawa and T. Honjo (ed.), Evolution of life. Springer-Verlag, Tokyo, Japan. 31. Cavalier-Smith, T. 1992. Origins of secondary metabolism. Ciba Found.
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Their sequences. Curr. Opin. Genet. Dev. 7:764?70. 70. Forterre, P., N. Benachenhou-Lahfa, F. Confalonieri, M. Duguet, C. Elie, and B. Labedan. 1992. The nature of the last universal ancestor and the root of the tree of life, still open questions. Biosystems 28:15?2. 71. Fox, G. E., E. Stackebrandt, R. B. Hespell, J. Gibson, J. Maniloff, T. A. Dyer, R. S. Wolfe, W. E. Balch, R. S. Tanner, L. J. Ma
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Of species by means of natural selection, or the preservation of favoured races in the struggle for life. John Murray, London, United Kingdom. 44. Davies, J. 1994. Inactivation of antibiotics and the dissemination of resistance genes. Science 264:375?82. 45. Deckert, G., P. V. Warren, T. Gaasterland, W. G. Young, A. L. Lenox, D. E. Graham, R. Overbeek, M. A. Snead, M. Keller, M. Aujay, R. Huber, R
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The latest. Figure 60 shows a significant increase in admissions among the elder groups along the five-year periods. The severity scores increased significantly as shown in Figure 61 (p
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Urse of the disease without the confounding effect of systemic adjuvant therapy), we restricted our next analyses of MFS to those 837 LNN disease patients who had not received (neo)adjuvant systemic therapy. The significant relationships of DC-SCRIPT as a continuous variable in these univariate analyses justified the use of the previously identified cut point that dichotomized the cohort in 33.3
1
Hựu vân, yếu đáo nhất tâm bất loạn cảnh giới, diệc vô tha thuật. Đây cũng là lời của đại sư Ngẫu Ích. Quý vị hy vọng niệm đến nhất tâm bất loạn, cũng không ngoài phương pháp này. Phương pháp đó là gì? Tối sơ hạ thủ, tu dụng số châu, ký đắc phân minh, khắc định khóa trình, quyết định vô khuyết, cửu cửu thuần thục, bất niệm tự niệm. Nhiên hậu ký số diệc đắc, bất ký sô diệc đắc. Tổ sư khuyên chúng ta
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Ms into six subfamilies (sf1 to sf6) based on their unique 3' terminal sequences, which were used to design 6 Taqman probes for quantitative real-time PCR [17]. With the exception of sf1, which detects the original BORIS form (B0) that was transfected into the cell lines, we measured the relative units of BORIS isoforms sf2 to sf6 in basal and BORIS-transfected MCF-7 and BCM1 cells. As shown in Fi
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Homologs: implications regarding origin of eukaryotic cells and of endoplasmic reticulum. Proc. Natl. Acad. Sci. USA 91:2895?899. 103. Gupta, R. S., K. Bustard, M. Falah, and D. Singh. 1997. Sequencing of heat shock protein 70 (DnaK) homologs from Deinococcus proteolyticus and Thermomicrobium roseum and their integration in a protein-based phylogeny of prokaryotes. J. Bacteriol. 179:345?57. 104. G
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On indicating that expression of tAg in trans fails to correct the replication defect of a tAgdeficient JCV genome. It is possible that the levels of tAg produced from the JCV transcriptional signals are insufficient to permit detection of a complementing activity. It should be noted that a similar mutation to the J domain of the MCV tAg did not alter DNA replication behavior, while the same mutat
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Rotein TCP-1 and the `chaperonin' family of bacterial (GroEL, 60-65 kDa heat shock antigen) and eukaryotic proteins. Biochem. Int. 20:833?41. 96. Gupta, R. S. 1995. Evolution of the chaperonin families (Hsp60, Hsp10 and Tcp-1) of proteins and the origin of eukaryotic cells. Mol. Microbiol. 15: 1?1. 97. Gupta, R. S. 1995. Phylogenetic analysis of the 90 kD heat shock family of protein sequences and
1
Sequence. J. Bacteriol. 176:7748?753. 57. Falah, M., and R. S. Gupta. 1997. Phylogenetic analysis of mycoplasmas based on Hsp70 sequences: cloning of the dnaK (hsp70) gene region of Mycoplasma capricolum. Int. J. Syst. Bacteriol. 47:38?5. 58. Felsenstein, J. 1982. Numerical methods for inferring evolutionary trees. Q. Rev. Biol. 57:379?04. 59. Felsenstein, J. 1985. Confidence limits in phylogenies
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Here comes the tummy yummy pizza…. the best hotspot pizza
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Other zinc finger proteins at a surface groove of C-terminal binding proteins. Mol Cell Biol 2006, 26:8159?172. 8. Thillainadesan G, Isovic M, Loney E, Andrews J, Tini M, Torchia J: Genome analysis identifies the p15ink4b tumor suppressor as a direct target of the ZNF217/CoREST complex. Mol Cell Biol 2008, 28:6066?077. 9. You A, Tong JK, Grozinger CM, Schreiber SL: CoREST is an integral component
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Sequence. J. Bacteriol. 176:7748?753. 57. Falah, M., and R. S. Gupta. 1997. Phylogenetic analysis of mycoplasmas based on Hsp70 sequences: cloning of the dnaK (hsp70) gene region of Mycoplasma capricolum. Int. J. Syst. Bacteriol. 47:38?5. 58. Felsenstein, J. 1982. Numerical methods for inferring evolutionary trees. Q. Rev. Biol. 57:379?04. 59. Felsenstein, J. 1985. Confidence limits in phylogenies
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Romogenic substrate (S-2302), specific for PK and FXIIa, was used to measure contact activation. Both strains exhibited PK/FXIIa activity on their surfaces (Fig. 1A). Interestingly, compared to the wild types, knockout of the M protein in these strains did not change PK/FXIIa activity significantly (Fig. 1A), suggesting that activation of contact system factors occurs independently of the M protei
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S and signature sequences: evolutionary relationships within prokaryotes and between prokaryotes and eukaryotes. Antonie Leeuwenhoek 72:49?1. 100. Gupta, R. S. 1998. Life's third domain (Archaea): an established fact or an endangered paradigm? A new proposal for classification of organisms based on protein sequences and cell structure. Theor. Popul. Biol. 54:91?104. 101. Gupta, R. S. 1998. What ar
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Acteria were removed, and hydrolysis of the substrate was measured at 405 nm. As a positive control, purified SK (pSK) was incubated in plasma, and the substrate was added directly. The results are shown as the means of at least three independent experiments with fresh frozen plasma from different donors the SD. n.s., not significant; **, P 0.01; ***, P 0.001; ****, P 0.0001.creased PK/FXIIa activ
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Ommon to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins. Proc. Natl. Acad. Sci. USA 89:7290?294. 18a.Brennan, P. J., and H. Nikaido. 1995. The envelope of mycobacteria. Annu. Rev. Biochem. 64:29?3. 19. Brooks, B. W., R. G. E. Murray, J. L. Johnson, E. Stackebrandt, C. R. Woese, and G. E. Fox. 1980. Red-pigmented micrococci: a basis for taxonomy. Int. J. Syst.
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