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E positively associated with tumor grade and ESR1, PGR, and ESR2 steroid hormone receptor expression level and negatively associated with invasive epithelial tumor cell content and tumor size. In addition, ESR2 was more highly expressed in tumors with a higher percentage of stromal cells (786 tumors with 30 to 70 invasive epithelial cells), and ESR1 wasSieuwerts et al. Breast Cancer Research 201
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Global X-ray inspection systems market size was US$ 687 Mn in 2019 and is expected to reach US$ XX Mn by 2027, at a CAGR of 7.7% during the forecast period.
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Urse of the disease without the confounding effect of systemic adjuvant therapy), we restricted our next analyses of MFS to those 837 LNN disease patients who had not received (neo)adjuvant systemic therapy. The significant relationships of DC-SCRIPT as a continuous variable in these univariate analyses justified the use of the previously identified cut point that dichotomized the cohort in 33.3
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Ransfection assays [11]. To determine if these proteins, together with BORIS, can form secondary complexes with each other in the absence of DNA and to understand better the mechanism underlying the regulation of MAGE-A1 expression, we carried out in vitro proteinprotein interaction assays. Each of the proteins was either a resin-bound "bait" fusion protein or a [35S]-L-methionine labeled "prey" p
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Ata for all admissions from 2000 to 2014, which allows us to study the evolution of severity scales and the clinical activity by age and type of patient. Objectives: To describe the effectiveness of severity scales used in our ICU over 15 years by age and type of patient. Methods: A retrospective, single-center and descriptive study was conducted from 2000 to 2014. All patients admitted consecutiv
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Ee plasmin and SK-plasmin complexes were inhibited by a specific plasmin inhibitor to avoid cross-reaction with the substrate. Hydrolysis was determined at 405 nm, and the M49 sample without inhibitor was set as 100 . The results are shown as means of at least three independent experiments with fresh frozen plasma from different donors (A) or pooled normal plasma (C and D) the SD. **, P 0.01; ***,
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Manuscript.Compliance with Ethical Standards Amgen Inc. conducted and funded all analyses. Amgen Inc. also provided funding for medical writing and editorial support to MedVal Scientific Information Services, LLC, Skillman, NJ, USA. This article does not contain any studies with human participants or animals performed by any of the authors. This paper was prepared according to the ICMJE Uniform Re
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Gnificant contribution to viral DNA replication activity, and furthermore, that its effect on agnoprotein phosphorylation status does not completely explain its role in replication, since agnoprotein was not present in our assay. We speculate that interactions of tAg with PP2A and Rb proteins alter JCV TAg phosphorylation status and promote cell cycle progression, leading to conditions more favora
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E positively associated with tumor grade and ESR1, PGR, and ESR2 steroid hormone receptor expression level and negatively associated with invasive epithelial tumor cell content and tumor size. In addition, ESR2 was more highly expressed in tumors with a higher percentage of stromal cells (786 tumors with 30 to 70 invasive epithelial cells), and ESR1 wasSieuwerts et al. Breast Cancer Research 201
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Ska), extracellular protein factor ( epf), or protein F2 ( prtF2) (B) were tested for surface PK/FXIIa activity after incubation with normal human plasma. (C) The PK/FXIIa activity at the surfaces of M49 wild-type and ska mutant strains was examined after exposure to normal or plasminogen-deficient plasma. Kaolin served as a positive control for plasmin-independent contact system activation. (D) P
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Homologs: implications regarding origin of eukaryotic cells and of endoplasmic reticulum. Proc. Natl. Acad. Sci. USA 91:2895?899. 103. Gupta, R. S., K. Bustard, M. Falah, and D. Singh. 1997. Sequencing of heat shock protein 70 (DnaK) homologs from Deinococcus proteolyticus and Thermomicrobium roseum and their integration in a protein-based phylogeny of prokaryotes. J. Bacteriol. 179:345?57. 104. G
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And Glycemic lability index (Exp(B) = 1.001) were significantly associated with mortality. The variables were subsequently compared beween the elderly patients (60 years) and those 60 years age Results: Multivariate logistic regression analysis was performed on variables found to be significantly associated with mortality. Age (Exp(B) = 1.735) ; APACHE Score (Exp(B) = 1.298) and Glycemic lability
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Ype and its ska mutant were incubated in normal or plasminogen-deficient plasma for 30 min. After incubation, unbound plasma proteins were removed and PK/FXIIa activity determined. Kaolin, a potent contact system activator, was used as a positive control (Fig. 1C). After incubation of M49 wild-type bacteria in plasminogen-deficient plasma, no PK/FXIIa activity was detectable (A405 0.11) compared t
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Recombinant human C1-INH preparation [rhC1-INH]), a plasma kallikrein inhibitor (ecallantide), a bradykinin B2 receptor antagonist (icatibant) and a synthetic attenuated androgen (danazol). In Europe, human plasma-derived C1-INH products have been used for more than three decades for the treatment of acute HAE, and icatibant and rhC1-INH have been approved since 2008 and 2010, respectively [27?9].
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Ype and its ska mutant were incubated in normal or plasminogen-deficient plasma for 30 min. After incubation, unbound plasma proteins were removed and PK/FXIIa activity determined. Kaolin, a potent contact system activator, was used as a positive control (Fig. 1C). After incubation of M49 wild-type bacteria in plasminogen-deficient plasma, no PK/FXIIa activity was detectable (A405 0.11) compared t
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Erity scales effectiveness by type of patients. Conclusions: We observed a decrease of effectiveness of severity scales over time, however this effectiveness remains optimal in all the severity scales except for MPM0.Fig. 61 (abstract A946).Intensive Care Medicine Experimental 2016, 4(Suppl 1):Page 485 ofObjective: To determine satisfaction amongst relatives of patients on our ICU. Methods: We dis
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N plasma (A) or plasma deficient in plasminogen (B). The chromogenic substrate S-2302, specific for PK/FXIIa, was added and, after incubation, hydrolysis was determined at 405 nm. (C) Plasmin activity was detected in normal and plasminogen-deficient plasma after incubation with supernatants from overnight cultures of M49 wild-type (M49) or ska mutant ( ska) strains or purified streptokinase (pSK).
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More susceptible to UTIs than are healthy patients because of the greater adherence of type 1 fimbriated E. coli to bladder cells (57). The LGI network of Candida Als and Epa adhesins N-Als1p has been shown to interact with fucose-containing glycans that are present in blood group antigens and preferentially with antigen Htype 2 (22). Therefore, we performed glycan array screening to also determin
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Nems (IMP/MER) was significantly reduced (DDD difference of -17 and -34 respectively), confirming a tendency in growth in the susceptibility profile of Pseudomonas aeruginosa. 3. Overall, the optimization of all groups of antibiotics and antifungals leads to saving 19 of the expenses.A943 The implantation of an antimicrobial stewardship programme in intensive care units is also possible. Ana
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